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Anti-SFRP1 Antibody EPR7003
Also for SFRP1 (NM_003012)
|A synthetic peptide corresponding to residues in human SFRP1 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
|WB, ASSAY, IHC
||WB: 1:1000 - 1:10000; IHC-P: 1:50 - 1:100
|Does not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC/IF or IP.|
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for Flow Cyt,ICC/IF or IP.
|Homo sapiens secreted frizzled-related protein 1 (SFRP1)|
|FRP; FRP-1; FRP1; FrzA; SARP2|
|SFRP1 is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. Members of this family act as soluble modulators of Wnt signaling; mutations in SFRP lead to deregulated activation of the Wnt-pathway, which is associated with cancer. SFRP1 is involved in determining the polarity of photoreceptor cells in the retina (1).|
Wnt Signaling Pathway
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Western blot - Anti-SFRP1 antibody [EPR7003]; All lanes : Anti-SFRP1 antibody [EPR7003] at 1/1000 dilution.Lane 1 : Human heart lysate.Lane 2 : MDA-MB-435 lysate.Lane 3 : A375 lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat Anti-rabbit HRP at 1/2000 dilution.Predicted band size : 35 kDa.
Other-Anti-SFRP1 antibody [EPR7003](ab126613); Equilibrium disassociation constant (KD)..
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-SFRP1 antibody [EPR7003]; ab126613, at 1/50 dilution, staining SFRP1 in Formalin-fixed, Paraffin-embedded Human heart muscle tissue by Immunohistochemistry.