OriGene Technologies, Inc.
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-PML antibodies

Anti-PML PHOSPHO Antibody EPR6151

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310766
  • Rabbit Monoclonal antibody against PML, pS518 (Phospho-specific)
100ul 325 In Stock
Add to Shopping Cart
WB(1)
IHC(2)

OriGene Data

ImmunogenA phospho specific peptide corresponding to residues surrounding Serine 518 of human PML was used as an immunogen. This antibody only detects PML phosphorylated at Serine 518.
Clone NameEPR6151 IsotypeIgG
Species ReactivityHuman, Mouse Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens promyelocytic leukemia (PML), transcript variant 11
Alternative NameMYL; PP8675; RNF71; TRIM19
Database LinkNP_150253
FunctionPML is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. PML is often involved with retinoic acid receptor alpha associated with acute promyelocytic leukemia (APL) (1).
Related Pathway

* Shipping is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-PML Protein (phospho S518) antibody [EPR6151]; All lanes : Anti-PML Protein (phospho S518) antibody [EPR6151] at 1/1000 dilution.Lane 1 : HeLa lysate (untreated).Lane 2 : HeLa lysate treated with Alkaline Phosphatase.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 110 kDa.Observed band size : 110 kDa.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PML Protein (phospho S518) antibody [EPR6151]; TA310766, at a 1/100 dilution, staining Human PML Protein in astrocytoma, using Immunohistochemistry, Formalin/PFA-fixed paraffin-emebedded tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-PML Protein (phospho S518) antibody [EPR6151]; TA310766, at a 1/50 dilution, staining Human PML Protein in breast carcinoma, using Immunohistochemistry, Formalin/PFA-fixed paraffin-emebedded tissue.

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title