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Home Antibody All anti-INHBB antibodies

Anti-INHBB Antibody EPR2788(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310631
  • Rabbit Monoclonal antibody against Inhibin beta B (INHBB)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC419476) , 20ug Explanation
100ul 325 3-7 Days
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WB(2)
Assay(1)
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Also for INHBB (NM_002193)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Inhibin beta B was used as an immunogen.
Clone NameEPR2788(2) IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000 - 1:10000
Predicted MW Explanation 45 kDa
BufferpH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens inhibin, beta B (INHBB)
Alternative NameMGC157939
Database LinkNP_002184
Entrez Gene 3625 Human
Entrez Gene 16324 Mouse
Entrez Gene 25196 Rat
FunctionThe inhibin beta B subunit joins the alpha subunit to form a pituitary FSH secretion inhibitor. Inhibin has been shown to regulate gonadal stromal cell proliferation negatively and to have tumor-suppressor activity. In addition, serum levels of inhibin have been shown to reflect the size of granulosa-cell tumors and can therefore be used as a marker for primary as well as recurrent disease. Because expression in gonadal and various extragonadal tissues may vary severalfold in a tissue-specific fashion, it is proposed that inhibin may be both a growth/differentiation factor and a hormone. Furthermore, the inhibin beta B subunit forms a homodimer, activin B, and also joins with the beta A subunit to form a heterodimer, activin AB, both of which stimulate FSH secretion (1).
Related PathwaySecreted ProteinDruggable Genome Cytokine-cytokine receptor interactionTGF-beta signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Inhibin beta B antibody [EPR2788(2)]; All lanes : Anti-Inhibin beta B antibody [EPR2788(2)] at 1/1000 dilution.Lane 1 : Mouse brain lysate.Lane 2 : Rat brain lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 45 kDa.Observed band size : 52 kDa .
WB Image
Western blot - Anti-Inhibin beta B antibody [EPR2788(2)]; Anti-Inhibin beta B antibody [EPR2788(2)] at 1/1000 dilution + Human Inhibin beta B recombinant protein (mature form: 17 kDa) (10 ng).Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 45 kDa.
Assay Image
Other-Anti-Inhibin beta B antibody [EPR2788(2)](TA310631); Equilibrium disassociation constant (KD)..

 

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