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Anti-IL22 Antibody EPR5740
Also for IL22 (NM_020525)
|A synthetic peptide corresponding to residues in human IL-22 was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000
|Does not react with Mouse, Rat. Is unsuitable for ICC/IF,IHC-P or IP.|
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for ICC/IF,IHC-P or IP.
|Homo sapiens interleukin 22 (IL22)|
|IL-21; IL-22; IL-D110; IL-TIF; ILTIF; TIFa; TIFIL-23; zcyto18|
|Interleukin-22 (IL-22), an IL-10 family cytokine, is expressed in activated T cells, Th1 cells and NK cells (1, 2). IL-22 induces expression of various antimicrobial peptides such as ß-defensins in skin, respiratory, and digestive tissues, which express IL-22R (1). It also mediates the crosstalk between leukocytes and tissue epithelia because its receptor is preferentially expressed on various tissue epithelial cells. IL-22 is essential for host defense against infections of extracellular pathogens, such as bacteria and yeasts, by eliciting various innate defensive mechanisms from tissue epithelial cells and promoting wound-healing responses (2). Enhanced IL-22 levels have been linked to various states of immunoactivation as seen in the context of infection, autoimmunity, and allergic disorders (3).|
Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
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Western blot - Anti-IL22 antibody [EPR5740]; Anti-IL22 antibody [EPR5740] at 1/1000 dilution + Recombinant Human IL22 at 0.01 µg.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 14 kDa.Observed band size : 20 kDa .
Other-Anti-IL22 antibody [EPR5740](ab124740); Equilibrium disassociation constant (KD)..