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Anti-IL17RA Antibody EPR1544(2)
Also for IL17RA (NM_014339)
|A synthetic peptide corresponding to residues in human IL-17R alpha was used as an immunogen.|
|Mouse, Human (Does not react with: Rat)
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, FC
||WB: 1:10000 - 1:50000; IP: 1:10 - 1:100; FC: 1:10 - 1:100
|pH: 7.40Preservative: 0.01% Sodium azide; Constituents: 50% Glycerol, 0.05% BSA|
|Is unsuitable for ICC/IF or IHC-P.
|Homo sapiens interleukin 17 receptor A (IL17RA), transcript variant 1|
|CANDF5; CD217; CDw217; hIL-17R; IL-17RA; IL17R|
Entrez Gene 23765 Human
Entrez Gene 16172 Mouse
|Interleukin-17R alpha is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. IL-17R alpha is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure (1).|
|TransmembraneDruggable Genome Cytokine-cytokine receptor interaction|
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Western blot - Anti-IL17A Receptor antibody [EPR1544(2)]; All lanes : Anti-IL17A Receptor antibody [EPR1544(2)] at 1/10000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : Raji cell lysate.Lane 3 : RAW264.7 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled Goat anti-rabbit at 1/2000 dilution.Predicted band size : 96 kDa.Observed band size : 125-158 kDa .
Other-Anti-IL17A Receptor antibody [EPR1544(2)](TA310619); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-IL17A Receptor antibody [EPR1544(2)]; Flow cytometric analysis of permeabilized HeLa cells labelling IL17A Receptor (red) with TA310619 at 1/10 and a rabbit IgG negative (green).