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Home Antibody All anti-IGF2R antibodies

Anti-IGF2R Antibody EPR6599

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310613
  • Rabbit Monoclonal antibody against IGF-2R (IGF2R)
100ul $325 3-7 Days
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WB(1)
IHC(2)
IF(1)
Assay(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus of human IGF-2R was used as an immunogen.
Clone NameEPR6599 IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB, ASSAY, IHC, IF Suggested DilutionsWB: 1:50000 - 1:200000; IP: 1:10 - 1:100; IHC-P: 1:250 - 1:500; FC: 1:100 - 1:500; ICC/IF: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens insulin-like growth factor 2 receptor (IGF2R)
Alternative NameCD222; CIMPR; M6P-R; MPR1; MPRI
Database LinkNP_000867
FunctionIGF-2R is a receptor for both insulin-like growth factor 2 (IGF-2) and mannose 6-phosphate (M6P). The IGF-2 and M6P binding sites are located on different segments of the receptor. This receptor functions in the intracellular trafficking of lysosomal enzymes, activation of transforming growth factor beta, and degradation of IGF-2. While mouse IGF-2R shows exclusive expression from the maternal allele, imprinting of human IGF-2R appears to be polymorphic, with only a minority of individuals showing expression from the maternal allele (1).
Related Pathway

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WB Image
Western blot - Anti-Mannose 6 Phosphate Receptor (Cation independent) antibody [EPR6599]; All lanes : Anti-Mannose 6 Phosphate Receptor (Cation independent) antibody [EPR6599] at 1/50000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : 293T cell lysate.Lane 3 : Caco-2 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 274 kDa.
Assay Image
Other-Anti-Mannose 6 Phosphate Receptor (Cation independent) antibody [EPR6599](TA310613); Equilibrium disassociation constant (KD)..
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mannose 6 Phosphate Receptor (Cation independent) antibody [EPR6599]; TA310613, at 1/250 dilution, staining Mannose 6 Phosphate Receptor (Cation independent) in paraffin-embedded Human papillary carcinoma tissue by Immunohistochemistry.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Mannose 6 Phosphate Receptor (Cation independent) antibody [EPR6599]; TA310613, at 1/250 dilution, staining Mannose 6 Phosphate Receptor (Cation independent) in Human tonsil tissue by Immunohistochemistry.
IF Image
Immunocytochemistry/ Immunofluorescence - Anti-Mannose 6 Phosphate Receptor (Cation independent) antibody [EPR6599]; TA310613, at 1/100 dilution, staining Mannose 6 Phosphate Receptor (Cation independent) in 293T cells by Immunofluorescence.

 

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