Home Antibody All anti-EphB3 antibodies
Anti-EphB3 Antibody EPR8280
Also for EphB3 (NM_004443)
|A synthetic peptide corresponding to residues in the extracellular domain of human EphB3 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, IF
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; FC: 1:10 - 1:100; ICC/IF: 1:100 - 1:250
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for IHC-P.
|Homo sapiens EPH receptor B3 (EPHB3)|
|ETK2; HEK2; TYRO6|
Entrez Gene 2049 Human
Entrez Gene 13845 Mouse
Entrez Gene 287989 Rat
|EphB3 is a receptor tyrosine kinase which binds promiscuously transmembrane ephrin-B family ligands residing on adjacent cells, leading to contact-dependent bidirectional singnaling into neighboring cells. It plays an important redundant role with other ephrin-B receptors in development and maturation of dendritic spines and the formation of excitatory synapses. EphB3 controls other aspects of development through regulation of cell migration and positioning. This includes angiogenesis, palate development and thymic epithelium development for instance. It also plays an important role in intestinal epithelium differentiation segregating progenitor from differentiated cells in the crypt (1). |
|Protein KinaseTransmembraneDruggable Genome Axon guidance|
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Western blot - Anti-Eph receptor B3 antibody [EPR8280]; All lanes : Anti-Eph receptor B3 antibody [EPR8280] at 1/1000 dilution.Lane 1 : Jurkat cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : HepG2 cell lysate.Lane 4 : MOLT4 cell lysate.Lane 5 : NIH3T3 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-Rabbit HRP at 1/2000 dilution.Predicted band size : 110 kDa.
Other-Anti-Eph receptor B3 antibody [EPR8280](TA310461); Equilibrium disassociation constant (KD)..
Immunocytochemistry/ Immunofluorescence - Anti-Eph receptor B3 antibody [EPR8280]; Immunocytochemical analysis of HeLa cells labelling Eph receptor B3 with TA310461 at 1/100.