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Anti-COMP Antibody EPR6289(2)
Also for COMP (NM_000095)
|A synthetic peptide corresponding to residues in human COMP was used as an immunogen.|
|Human, Mouse, Rat
||Lot dependent; please refer to CoA along with shipment
|WB, ASSAY, FC
||WB: 1:10000 - 1:50000; IHC-P: Use at an assay dependent concentration; FC: 1:10 - 1:100; ICC/IF: Use at an assay dependent concentration
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA
|Tissue culture supernatant
|Is unsuitable for IP.
|Homo sapiens cartilage oligomeric matrix protein (COMP)|
|EDM1; EPD1; MED; PSACH; THBS5|
|COMP is a noncollagenous extracellular matrix (ECM) protein. It consists of five identical glycoprotein subunits, each with EGF-like and calcium-binding (thrombospondin-like) domains. Oligomerization results from formation of a five-stranded coiled coil and disulfides. Binding to other ECM proteins such as collagen appears to depend on divalent cations. Mutations can cause the osteochondrodysplasias pseudoachondroplasia (PSACH) and multiple epiphyseal dysplasia (MED) (1).|
TGF Beta Signaling Pathway
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Western blot - Anti-COMP antibody [EPR6289(2)]; All lanes : Anti-COMP antibody [EPR6289(2)] at 1/10000 dilution.Lane 1 : Raji cell lysate.Lane 2 : BxPC3 cell lysate.Lane 3 : Saos 2 cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit IgG at 1/2000 dilution.Predicted band size : 82 kDa.
Other-Anti-COMP antibody [EPR6289(2)](TA310341); Equilibrium disassociation constant (KD)..
Flow Cytometry - Anti-COMP antibody [EPR6289(2)]; TA310341 at 1/10 dilution staining COMP in permeabilized Raji cells by Flow cytometry (red). Rabbit IgG negative control (green)