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Home Antibody All anti-CFB antibodies

Anti-CFB Antibody EPR9288(B)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA310318
  • Rabbit Monoclonal antibody against Complement Factor B (CFB)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400641) , 20ug Explanation
100ul 325 3-7 Days
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WB(1)
Assay(1)
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Also for CFB (NM_001710)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues on the C-terminus in human Complement Factor B was used as an immunogen.
Clone NameEPR9288(B) IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, ASSAY Suggested DilutionsWB: 1:1000 - 1:10000
BufferDoes not react with Mouse, Rat. Is unsuitable for IHC-P or IP.
Purification pH: 7.20
Preservative: 0.01% Sodium azide
Constituents: 48% PBS, 50% Glycerol, 0.05% BSA
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens complement factor B (CFB)
Alternative NameAHUS4; ARMD14; BF; BFD; CFAB; CFBD; FB; FBI12; GBG; H2-Bf; PBF2
Database LinkNP_001701
Entrez Gene 629 Human
FunctionComplement Factor B is a component of the alternative pathway of complement activation. Factor B circulates in the blood as a single chain polypeptide. Upon activation of the alternative pathway, it is cleaved by complement factor D yielding the noncatalytic chain Ba and the catalytic subunit Bb. The active subunit Bb is a serine protease that associates with C3b to form the alternative pathway C3 convertase. Bb is involved in the proliferation of preactivated B lymphocytes, while Ba inhibits their proliferation. Complement Factor B is linked to major histocompatibility complex (MHC) class III and is involved in the regulation of the immune reaction. Mutations in Complement Factor B are associated with a reduced risk of age-related macular degeneration (1).
Related Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Anti-Complement factor B antibody [EPR9288(B)]; All lanes : Anti-Complement factor B antibody [EPR9288(B)] at 1/1000 dilution.Lane 1 : Human serum lysate.Lane 2 : Human plasma lysate.Lysates/proteins at 10 ug per lane.Secondary.Goat anti-rabbit HRP conjugated antibody at 1/2000 dilution.Predicted band size : 86 kDa.Observed band size : 95 kDa .Additional bands at : 60 kDa (possible isoform).
Assay Image
Other-Anti-Complement factor B antibody [EPR9288(B)](TA310318); Equilibrium disassociation constant (KD)..

 

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