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Anti-BGLAP Antibody EPR3690
Also for BGLAP (NM_199173)
|A synthetic peptide corresponding to residues in human Osteocalcin was used as an immunogen.|
||Tissue culture supernatant
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000
|Does not react with Mouse, Rat. Is unsuitable for IHC-P or IP.|
Preservative: 0.01% Sodium azide
Constituents: 49% PBS, 50% Glycerol, 0.05% BSA (Protein A or G Sepharose)
|Is unsuitable for IHC-P or IP.
|Homo sapiens bone gamma-carboxyglutamate (gla) protein (BGLAP)|
|BGP; OC; OCN|
|Osteocalcin, a vitamin K-dependent protein, constitutes 1-2% of total bone protein, and it binds strongly to apatite and calcium (1, 2). Thus, Osteocalcin is involved in bone extracellular matrix mineralization and bone formation (2, 3). Moreover, it exists in serum as fully carboxylated or partially carboxylated forms and completely uncarboxylated. Uncarboxylated Osteocalcin promotes insulin secretion, insulin gene expression and insulin sensitivity (4). In addition, it acts as a hormone with a complex cross-talk between adipose tissue and the skeleton (3).|
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Western blot - Anti-Osteocalcin antibody; Anti-Osteocalcin [EPR3690] antibody at 1/1000 dilution + Human Osteocalcin recombinant protein at 0.01 µg.Predicted band size : 11 kDa.