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Anti-ACTB Antibody Clone 8H10, Loading Control


Specifications Citations (4) Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA310155 Mouse monoclonal anti-ACTB(beta Actin) antibody, Loading control 100ul $248 In Stock
LC420311 ACTB HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenBeta-actin N-terminal peptide-KLH conjugates
Clone NameClone 8H10 IsotypeIgG
Species ReactivityHuman, Mouse, Rat, Monkey, Dog Concentration1mg/ml
Guaranteed Application *WB Suggested DilutionsWB 1:1000 - 1:10000
BufferPBS, pH 7.4 with 0.05% sodium azide.
Purification Affinity purified

Reference Data

Target NameHomo sapiens actin, beta (ACTB)
Alternative NameBRWS1; PS1TP5BP1
Database LinkNP_001092
Entrez Gene 60 Human
Entrez Gene 11461 Mouse
Entrez Gene 81822 Rat
Entrez Gene 574285 Monkey
Entrez Gene 403580 Dog
FunctionActins are highly conserved proteins that are involved in cell motility, structure and integrity, processes that are crucial for tissue development and the development of organism. The actin cytoskeleton is one of the principal drivers of cell motility and is capable of responding to complex signaling cascades. Recent evidence suggests that it may play key roles in regulating apoptosis and aging. beta actin is one of six different actin isoforms which have been identified. Like GAPDH, ?-actin is constitutively expressed at high levels in almost all tissues and cell lines making it ideal for use as a loading control marker in immunoblots.
Related PathwayES Cell Differentiation/IPS Focal adhesionAdherens junctionTight junctionLeukocyte transendothelial migrationRegulation of actin cytoskeletonVibrio cholerae infectionMore Pathways >>

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of extracts (35ug) from 9 different cell lines by using anti-beta-Actin monoclonal antibody (HepG2: human; HeLa: human; SVT2: mouse; A549: human; COS7: monkey; Jurkat: human; MDCK: canine; PC12: rat; MCF7: human).
Figure from citation: Western Blot of ACTB(beta-actin) protein level by using anti-ACTB antibody in rat lung fibroblasts. Dilution: 1:1000 View Citation
Figure from citation: Western Blot of ACTB(beta-actin) protein level by using anti-ACTB antibody in normal human uveal (control) and human uveal melanoma (UM) samples. Dilution: 1:1000 View Citation


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