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Home Antibody All anti-DNMT3L antibodies

Anti-DNMT3L Antibody S117-9

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA309323
  • Mouse Monoclonal anti-DNMT3L Antibody
  • FREE positive control: HEK293T cell transient overexpression lysate (LC402250) , 20ug
100ug $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenFusion protein amino acids 1-387 of human DNMT3L, accession number BAA95556
Clone NameS117-9 IsotypeIgG1
Species ReactivityHuman Concentration1mg/mL
Guaranteed Application *WB Suggested DilutionsWB, ICC, IP
BufferPBS pH7.0, 50% glycerol, 0.09% sodium azide

Reference Data

Target NameHomo sapiens DNA (cytosine-5-)-methyltransferase 3-like, transcript variant 2 (cDNA clone MGC:1090 IMAGE:3138514), complete cds
Alternative NameMGC1090; cytosine-5-methyltransferase 3-like protein; human cytosine-5-methyltransferase 3-like protein; DNA (cytosine-5-)-methyltransferase 3-like
Database LinkAAH02560
FunctionCpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein with similarity to DNA methyltransferases. This protein is not thought to function as a DNA methyltransferase as it does not contain the amino acid residues necessary for methyltransferase activity. However, this protein does stimulate de novo methylation by DNA cytosine methyltransferase 3 alpha and it is thought to be required for the establishment of maternal genomic imprints. This protein also mediates transcriptional repression through interaction with histone deacetylase 1. Alternative splicing results in two transcript variants. An additional splice variant has been described but its biological validity has not been determined. [provided by RefSeq].
Related Pathway

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WB Image
Western blot analysis of DNMT3L in a human tissue mix using a 1:1000 dilution of anti-DNMT3L

 

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