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Home Antibody All anti-AP1S2 antibodies

Anti-AP1S2 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA308977 Rabbit polyclonal antibody to AP1S2 (adaptor-related protein complex 1, sigma 2 subunit) 100ul $325 3-7 Days
LC418354 AP1S2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IF(1)

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 157 of AP1S2 (Uniprot ID#P56377)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Rat, Chimpanzee) Concentration0.53mg/ml
Guaranteed Application *WB, IF Suggested DilutionsICC/IF:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 19kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Rat (100%), Chimpanzee (100%)

Reference Data

Target NameHomo sapiens adaptor-related protein complex 1, sigma 2 subunit (AP1S2), transcript variant 2
Alternative NameDC22; MRX59; MRXS21; MRXS5; MRXSF; PGS; SIGMA1B
Database LinkNP_003907
Entrez Gene 8905 Human
Entrez Gene 302671 Rat
FunctionAdaptor protein complex 1 is found at the cytoplasmic face of coated vesicles located at the Golgi complex, where it mediates both the recruitment of clathrin to the membrane and the recognition of sorting signals within the cytosolic tails of transmembrane receptors. This complex is a heterotetramer composed of two large, one medium, and one small adaptin subunit. The protein encoded by this gene serves as the small subunit of this complex and is a member of the adaptin protein family. Transcript variants utilizing alternative polyadenylation signals exist for this gene. [provided by RefSeq]
Related PathwayDruggable Genome Lysosome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample (30 ug of whole cell lysate). A: Raji. 12% SDS PAGE. TA308977 diluted at 1:1000.
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Confocal immunofluorescence analysis (Olympus FV10i) of methanol-fixed HeLa, using AP1S2(TA308977) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:2000.
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