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Anti-LTBP4 Antibody


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SKU Description Amount Price Availability*  
  • Rabbit Polyclonal antibody to LTBP4 (latent transforming growth factor beta binding protein 4)
100ul 325 3-7 Days
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Also for LTBP4 (NM_001042545)
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 101 and 323 of LTBP4 (Uniprot ID#Q8N2S1)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 169kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens latent transforming growth factor beta binding protein 4 (LTBP4), transcript variant 3
Alternative NameARCL1C; LTBP-4; LTBP4L; LTBP4S
Database LinkNP_001036010
Entrez Gene 8425 Human
Entrez Gene 108075 Mouse
FunctionTransforming growth factor-beta, or TGFB (see TGFB1; MIM 190180), remains biologically latent after secretion, blocked from activity by its N-terminal propeptide (the latency-associated peptide, or LAP). TGFB is activated by its dissociation from LAP. The latent form of TGFB is secreted in association with a latent TGFB-binding protein, or LTBP (see LTBP1; MIM 150390), and assembled into the extracellular matrix. LTBPs are mainly composed of epidermal growth factor (EGF; MIM 131530)-like repeats and protein domains with 8-cysteine repeats, both of which are also found in fibrillins (e.g., MIM 134797). See Oklu and Hesketh (2000) [PubMed 11104663] for a review of the LTBP gene family.[supplied by OMIM]
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
LTBP4 antibody [N1N2], N-term detects LTBP4 protein by Western blot analysis. A. 30 ug K562 whole cell lysate/extract. 5 % SDS-PAGE. LTBP4 antibody [N1N2], N-term (TA308967) dilution: 1:1000
WB Image
Sample (50 ug of whole cell lysate). A: Mouse brain. 5% SDS PAGE. TA308967 diluted at 1:1000.
IHC Image
LTBP4 antibody [N1N2], N-term detects LTBP4 protein at cytosol on Adrenal Gland Tumor by immunohistochemical analysis. Sample: Paraffin-embedded Adrenal Gland Tumor. LTBP4 antibody [N1N2], N-term (TA308967) dilution: 1:250.
IF Image
Immunofluorescence analysis of methanol-fixed A431, using LTBP4(TA308967) antibody at 1:200 dilution.


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