Home Antibody All anti-F7 antibodies
|Recombinant fragment corresponding to a region within amino acids 209 and 466 of Factor VII (Uniprot ID#P08709)|
|Human, Mouse (Predicted: Monkey)
|0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.|
|Purified by antigen-affinity chromatography.
|Seq homology of immunogen across species: Monkey (91%)
|Homo sapiens coagulation factor VII (serum prothrombin conversion accelerator) (F7), transcript variant 1|
Entrez Gene 2155 Human
Entrez Gene 14068 Mouse
Entrez Gene 721933 Monkey
|This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form, and is converted to an active form by either factor IXa, factor Xa, factor XIIa, or thrombin by minor proteolysis. Upon activation of the factor VII, a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated, and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions, the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy. [provided by RefSeq]|
|ProteaseDruggable Genome Complement and coagulation cascades|
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Sample(30 ug of whole cell lysate). A:H1299. 7.5% SDS PAGE. TA308874 diluted at 1:500
Sample (30 ug of whole cell lysate). . A:NIH-3T3. 10% SDS PAGE. . TA308874 diluted at 1:1000.
Immunohistochemical analysis of paraffin-embedded normal gastric epithelium (gland) , using F7(TA308874) antibody at 1:100 dilution.