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Home Antibody All anti-BMPR2 antibodies

Anti-BMPR2 Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308587
  • Rabbit polyclonal antibody to BMPR2 (bone morphogenetic protein receptor, type II (serine/threonine kinase))
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC420077) , 20ug Explanation
100ul 325 In Stock
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WB(2)
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Also for BMPR2 (NM_001204)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 667 and 951 of BMPR2 (Uniprot ID#Q13873)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Pig) Concentration0.89mg/ml
Guaranteed Application *WB Suggested DilutionsWB:1:500-1:3000
Predicted MW Explanation 115kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Pig (92%)

Reference Data

Target NameHomo sapiens bone morphogenetic protein receptor, type II (serine/threonine kinase) (BMPR2)
Alternative NameBMPR-II; BMPR3; BMR2; BRK-3; POVD1; PPH1; T-ALK
Database LinkNP_001195
Entrez Gene 659 Human
Entrez Gene 12168 Mouse
FunctionThis gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of two different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. Mutations in this gene have been associated with primary pulmonary hypertension, both familial and fenfluramine-associated, and with pulmonary venoocclusive disease. [provided by RefSeq]
Related PathwayProtein KinaseTransmembraneDruggable Genome Cytokine-cytokine receptor interactionTGF-beta signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample(30 ug of whole cell lysate). A:H1299. B:Raji . 7.5% SDS PAGE. TA308587 diluted at 1:1000
WB Image
Sample (30 ug of whole cell lysate). . A:NIH-3T3. 7.5% SDS PAGE. . TA308587 diluted at 1:1000.

 

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