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Home Antibody All anti-ACVR2A antibodies

Anti-ACVR2A Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308578
  • Rabbit Polyclonal antibody to Activin A Receptor type IIA (activin A receptor, type IIA)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC419844) , 20ug
100ul 325 In Stock
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Also for ACVR2A (NM_001616)
cDNA Clone shRNA/siRNA Lysate Protein Request Antibody

OriGene Data

ImmunogenRecombinant protein fragment contain a sequence corresponding to a region within amino acids 267 and 509 of Human ACVR2A
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB:1:5000-1:20000;
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens activin A receptor, type IIA (ACVR2A), transcript variant 2
Alternative NameACTRII; ACVR2
Database LinkNP_001607
FunctionThis gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases. [provided by RefSeq]
Related Pathway
Cytokine-cytokine receptor interaction
TGF Beta Signaling Pathway

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A: Hela B: HepG2 (anti-ACVR2A antibody diluted at 1:10000)

 

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