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Home Antibody All anti-ADRA1A antibodies

Anti-ADRA1A Antibody

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SKU Description Amount Price Availability*  
TA308493
  • Rabbit Polyclonal antibody to alpha 1a Adrenergic Receptor (adrenergic, alpha-1A-, receptor)
100ul $325 3-7 Days
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WB(2)
IHC(3)
IF(1)

OriGene Data

ImmunogenSynthetic peptide contain a sequence corresponding to a region within amino acids 206 and 260 of alpha 1a Adrenergic Receptor (Uniprot ID#P35348)
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Bovine, Dog, Guinea pig, Pig, Rabbit, Rhesus Monkey) Concentration1.03mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 52kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Dog (100%), Pig (100%), Rabbit (100%), Rhesus Monkey (100%), Bovine (100%), Guinea pig (100%)

Reference Data

Target NameHomo sapiens adrenoceptor alpha 1A (ADRA1A), transcript variant 1
Alternative NameADRA1C; ADRA1L1; ALPHA1AAR
Database LinkNP_000671
Entrez Gene 148 Human
Entrez Gene 712509 Monkey
Entrez Gene 403866 Dog
FunctionAlpha-1-adrenergic receptors (alpha-1-ARs) are members of the G protein-coupled receptor superfamily. They activate mitogenic responses and regulate growth and proliferation of many cells. There are 3 alpha-1-AR subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. This gene encodes alpha-1A-adrenergic receptor. Alternative splicing of this gene generates four transcript variants, which encode four different isoforms with distinct C-termini but having similar ligand binding properties. [provided by RefSeq]
Related PathwayGPCRTransmembraneDruggable Genome Calcium signaling pathwayNeuroactive ligand-receptor interactionVascular smooth muscle contraction

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

alpha 1a Adrenergic Receptor antibody detects alpha 1a Adrenergic Receptor protein by western blot analysis. A. 30 ug Jurkat whole cell lysate/extract. B. 30 ug Raji whole cell lysate/extract. C. 30 ug NCI-H929 whole cell lysate/extract. 10 % SDS-PAGE. al
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Sample(30 ug of whole cell lysate). A:Raji . 10% SDS PAGE. TA308493 diluted at 1:1000
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Immunohistochemical analysis of paraffin-embedded Heart, using alpha 1a Adrenergic Receptor(TA308493) antibody(10 ug/ml).
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alpha 1a Adrenergic Receptor antibody detects alpha 1a Adrenergic Receptor protein at cytosol on mouse prostate by immunohistochemical analysis. Sample: Paraffin-embedded mouse prostate. alpha 1a Adrenergic Receptor antibody (TA308493) dilution: 1:500.
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alpha 1a Adrenergic Receptor antibody detects alpha 1a Adrenergic Receptor protein at cytosol on rat hind brain by immunohistochemical analysis. Sample: Paraffin-embedded rat hind brain. alpha 1a Adrenergic Receptor antibody (TA308493) dilution: 1:500.
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Immunofluorescence analysis of methanol-fixed Hep3B, using alpha 1a Adrenergic Receptor(TA308493) antibody at 1:500 dilution.
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