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Anti-SCYE1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA308323 Rabbit polyclonal antibody to EMAP II (small inducible cytokine subfamily E, member 1 (endothelial monocyte-activating)) 100ul $325 In Stock
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Also for SCYE1 (NM_004757)
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OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 1 and 263 of AIMP1 (Uniprot ID#Q12904)
Clone Name IsotypeIgG
Species ReactivityHuman Concentration0.54mg/ml
Guaranteed Application *WB, IHC, IF Suggested DilutionsICC/IF:1:100-1:1000; IHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 34kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.

Reference Data

Target NameHomo sapiens aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 (AIMP1), transcript variant 1
Alternative NameEMAP2; EMAPII; HLD3; p43; SCYE1
Database LinkNP_004748
Entrez Gene 9255 Human
FunctionThe protein encoded by this gene is a cytokine that is specifically induced by apoptosis, and it is involved in the control of angiogenesis, inflammation, and wound healing. The release of this cytokine renders the tumor-associated vasculature sensitive to tumor necrosis factor. The precursor protein is identical to the p43 subunit, which is associated with the multi-tRNA synthetase complex, and it modulates aminoacylation activity of tRNA synthetase in normal cells. This protein is also involved in the stimulation of inflammatory responses after proteolytic cleavage in tumor cells. Multiple transcript variants encoding different isoforms have been found for this gene. A pseudogene has been identified on chromosome 20. [provided by RefSeq]
Related PathwayDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Sample(30 ug of whole cell lysate). A:H1299. B:Hep G2. 12% SDS PAGE. TA308323 diluted at 1:1000
AIMP1 antibody detects SCYE1 protein at cytosol on H1299 xenograft by immunohistochemical analysis. Sample: Paraffin-embedded H1299 xenograft. AIMP1 antibody (TA308323) dilution: 1:500.
Confocal immunofluorescence analysis (Olympus FV10i) of paraformaldehyde-fixed HeLa, using AIMP1(TA308323) antibody (Green) at 1:500 dilution. Alpha-tubulin filaments were labeled with anti-alpha tubulin antibody (Red) at 1:2000.


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