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Home Antibody All anti-ACMSD antibodies

Anti-ACMSD Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA308027
  • Rabbit Polyclonal antibody to ACMSD (aminocarboxymuconate semialdehyde decarboxylase)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC408707) , 20ug Explanation
100ul 325 3-7 Days
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WB(2)
IHC(1)
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Also for ACMSD (NM_138326)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenRecombinant fragment corresponding to a region within amino acids 105 and 336 of ACMSD (Uniprot ID#Q8TDX5)
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse (Predicted: Bovine) Concentration1mg/ml
Guaranteed Application *WB, IHC Suggested DilutionsIHC:1:100-1:1000; WB:1:500-1:3000
Predicted MW Explanation 38kDa
Buffer0.1M Tris, 0.1M Glycine, 10% Glycerol (pH7). 0.01% Thimerosal was added as a preservative.
Purification Purified by antigen-affinity chromatography.
Note Seq homology of immunogen across species: Bovine (93%)

Reference Data

Target NameHomo sapiens aminocarboxymuconate semialdehyde decarboxylase (ACMSD)
Alternative Name2-amino-3-carboxymuconate-6-semialdehyde decarboxylase; OTTHUMP00000162500; aminocarboxymuconate semialdehyde decarboxylase
Database LinkNP_612199
Entrez Gene 130013 Human
Entrez Gene 266645 Mouse
FunctionThe neuronal excitotoxin quinolinate is an intermediate in the de novo synthesis pathway of NAD from tryptophan, and has been implicated in the pathogenesis of several neurodegenerative disorders. Quinolinate is derived from alpha-amino-beta-carboxy-muconate-epsilon-semialdehyde (ACMS). ACMSD (ACMS decarboxylase; EC 4.1.1.45) can divert ACMS to a benign catabolite and thus prevent the accumulation of quinolinate from ACMS.[supplied by OMIM]
Related PathwayTransmembrane Tryptophan metabolismMetabolic pathways

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Sample (50 ug of whole cell lysate). A: Mouse brain. 10% SDS PAGE. TA308027 diluted at 1:1000.
WB Image
Sample (30 ug of whole cell lysate). A: Molt-4 . B: Raji. 10% SDS PAGE. TA308027 diluted at 1:1000.
IHC Image
Immunohistochemical analysis of paraffin-embedded SAS xenograft, using ACMSD(TA308027) antibody at 1:100 dilution.

 

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