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Home Antibody All anti-SFRP2 antibodies

Anti-SFRP2 Antibody EPR4832


Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against SFRP2(clone EPR4832)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC401053) , 20ug Explanation
100ul 325 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human SFRP2 was used as an immunogen.
Clone NameEPR4832 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
Predicted MW Explanation 33 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens secreted frizzled-related protein 2 (SFRP2)
Alternative NameFRP-2; SARP1; SDF-5
Database LinkNP_003004
Entrez Gene 6423 Human
Entrez Gene 20319 Mouse
Entrez Gene 310552 Rat
FunctionSFRP’s (Secreted Frizzled Related Proteins) function as soluble modulators of Wnt signaling. SFRP2 is a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. (1). It has a role in regulating cell growth and differentiation in specific cell types. Another function of SFRP2 is to regulate procollagen processing by binding to Tolloid metalloproteinases; it also interacts with an integrin-fibronectin complex modulating apoptosis (2). SFRP2 may be important for eye retinal development and for myogenesis (3). In addition, methylation of SFRP2 is a potential marker for the presence of colorectal cancer (1).
Related PathwaySecreted Protein Wnt signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - SFRP2 antibody [EPR4832]; All lanes : Anti-SFRP2 antibody [EPR4832] at 1/1000 dilution.Lane 1 : U87-MG cell lysate.Lane 2 : HUVEC cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit. at 1/2000 dilution.Predicted band size : 33 kDa.


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