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Home Antibody All anti-ACVRL1 antibodies

Anti-ACVRL1 Antibody EPR4074


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA307766 Rabbit monoclonal antibody against ACVRL1(clone EPR4074) 100ul $325 In Stock
LC400003 ACVRL1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human ACVRL1 was used as an immunogen.
Clone NameEPR4074 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
Predicted MW Explanation 56 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant

Reference Data

Target NameHomo sapiens activin A receptor type II-like 1 (ACVRL1), transcript variant 1
Alternative NameACVRLK1; ALK-1; ALK1; HHT; HHT2; ORW2; SKR3; TSR-I
Database LinkNP_000011
Entrez Gene 94 Human
Entrez Gene 11482 Mouse
Entrez Gene 25237 Rat
FunctionACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. The protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in ACVRL1 are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.
Related PathwayProtein KinaseTransmembraneDruggable Genome Cytokine-cytokine receptor interactionTGF-beta signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - ACVRL1 antibody [EPR4074]; All lanes : Anti-ACVRL1 antibody [EPR4074] at 1/1000 dilution.Lane 1 : JAR cell lysate.Lane 2 : Daudi cell lysate.Lane 3 : Jurkat cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 56 kDa.


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