Home Antibody All anti-FBP1 antibodies
Anti-FBP1 Antibody EPR4620
Also for FBP1 (NM_000507)
|A synthetic peptide corresponding to residues in human FBP1 was used as an immunogen.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC: 1:100 - 1:250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt or IHC-P.
|Homo sapiens fructose-1,6-bisphosphatase 1 (FBP1), transcript variant 1|
Entrez Gene 2203 Human
Entrez Gene 14121 Mouse
Entrez Gene 24362 Rat
|FBP1 (Fructose-1,6-bisphosphatase 1) is a gluconeogenesis regulatory enzyme that catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate (1). FBP1 catalyzes the removal of phosphate-1 from fructose 1,6-bisphosphate to produce fructose 6-phosphate, an important precursor in various biosynthetic pathways. It is a key, rate-controlling enzyme of gluconeogenesis, an important metabolic pathway that allows the cells to synthesize glucose and grow on non-carbohydrate carbon sources, such as glycerol, organic acids and amino acids (2). Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis (1).|
|Stem cell - PluripotencyDruggable Genome Glycolysis / GluconeogenesisPentose phosphate pathwayFructose and mannose metabolismMetabolic pathwaysInsulin signaling pathway|
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Western blot - FBP1 antibody [EPR4620]; All lanes : Anti-FBP1 antibody [EPR4620] at 1/1000 dilution.Lane 1 : Human stomach lysate.Lane 2 : Human fetal liver lysate.Lane 3 : MCF7 lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 37 kDa.