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Anti-FBP1 Antibody EPR4620


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SKU Description Amount Price Availability*  
  • Rabbit monoclonal antibody against FBP1(clone EPR4620)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424655) , 20ug Explanation
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human FBP1 was used as an immunogen.
Clone NameEPR4620 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; ICC: 1:100 - 1:250
Predicted MW Explanation 37 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt or IHC-P.

Reference Data

Target NameHomo sapiens fructose-1,6-bisphosphatase 1 (FBP1), transcript variant 1
Alternative NameFBP
Database LinkNP_000498
Entrez Gene 2203 Human
Entrez Gene 14121 Mouse
Entrez Gene 24362 Rat
FunctionFBP1 (Fructose-1,6-bisphosphatase 1) is a gluconeogenesis regulatory enzyme that catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate and inorganic phosphate (1). FBP1 catalyzes the removal of phosphate-1 from fructose 1,6-bisphosphate to produce fructose 6-phosphate, an important precursor in various biosynthetic pathways. It is a key, rate-controlling enzyme of gluconeogenesis, an important metabolic pathway that allows the cells to synthesize glucose and grow on non-carbohydrate carbon sources, such as glycerol, organic acids and amino acids (2). Fructose-1,6-diphosphatase deficiency is associated with hypoglycemia and metabolic acidosis (1).
Related PathwayStem cell - PluripotencyDruggable Genome Glycolysis / GluconeogenesisPentose phosphate pathwayFructose and mannose metabolismMetabolic pathwaysInsulin signaling pathway

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* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - FBP1 antibody [EPR4620]; All lanes : Anti-FBP1 antibody [EPR4620] at 1/1000 dilution.Lane 1 : Human stomach lysate.Lane 2 : Human fetal liver lysate.Lane 3 : MCF7 lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 37 kDa.


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