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Home Antibody All anti-CTNND1 antibodies

Anti-CTNND1 PHOSPHO Antibody EPR2380

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307608
  • Rabbit monoclonal antibody against p120 Catenin Phospho (pS268) (clone EPR2380 ) (Phospho-Specific)
100ul 325 In Stock
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WB(1)
IHC(1)
IF(1)

OriGene Data

ImmunogenA phospho-specific peptide corresponding to residues surrounding serine 268 of human p120 Catenin was used as an immunogen. The antibody only detects p120 Catenin phosphorylated on serine 268.
Clone NameEPR2380 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, IF Suggested DilutionsWB: 1:2500 - 1:5000; IHC-P: 1:100 - 1:250; ICC/IF: 1:100 - 1:250
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt or IP.

Reference Data

Target NameHomo sapiens catenin (cadherin-associated protein), delta 1 (CTNND1), transcript variant 3
Alternative NameCAS; CTNND; p120; p120(CAS); p120(CTN); P120CAS; P120CTN
Database LinkNP_001322
FunctionCatenins are proteins that are linked to the cytoplasmic domain of transmembrane cadherins. p120 Catenin is one member of this Armadillo gene family of junctional plaque proteins (1-3). The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be important for cadherins cell-adhesion properties. Recently it became clear that some catenins also mediate nuclear signaling (1). p120 Catenin is implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors.
Related Pathway
Adherens junction
EGFR1 Signaling Pathway
Wnt Signaling Pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - delta 1 Catenin (phospho S268) antibody [EPR2380]; All lanes : Anti-delta 1 Catenin (phospho S268) antibody [EPR2380] at 1/5000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : HeLa cell lysate treated with Calyculin A.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 108 kDa.Observed band size : 90-120 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - delta 1 Catenin (phospho S268) antibody [EPR2380]; TA307608 at 1/100 dilution staining delta 1 Catenin in paraffin-embedded human breast carcinoma tissue by Immunohistochemistry.
IF Image
Immunocytochemistry/ Immunofluorescence - delta 1 Catenin (phospho S268) antibody [EPR2380]; Immunofluorescent staining of delta 1 Catenin in A431 cells using TA307608 at 1/100 dilution.

 

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