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Anti-CTNND1 PHOSPHO Antibody EPR2380
Also for CTNND1 (NM_001331)
|A phospho-specific peptide corresponding to residues surrounding serine 268 of human p120 Catenin was used as an immunogen. The antibody only detects p120 Catenin phosphorylated on serine 268.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||WB: 1:2500 - 1:5000; IHC-P: 1:100 - 1:250; ICC/IF: 1:100 - 1:250
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for Flow Cyt or IP.
|Homo sapiens catenin (cadherin-associated protein), delta 1 (CTNND1), transcript variant 3|
|CAS; CTNND; p120; p120(CAS); p120(CTN); P120CAS; P120CTN|
Entrez Gene 1500 Human
|Catenins are proteins that are linked to the cytoplasmic domain of transmembrane cadherins. p120 Catenin is one member of this Armadillo gene family of junctional plaque proteins (1-3). The association of catenins to cadherins produces a complex which is linked to the actin filament network, and which seems to be important for cadherins cell-adhesion properties. Recently it became clear that some catenins also mediate nuclear signaling (1). p120 Catenin is implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. |
|Druggable Genome Adherens junctionLeukocyte transendothelial migration|
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Western blot - delta 1 Catenin (phospho S268) antibody [EPR2380]; All lanes : Anti-delta 1 Catenin (phospho S268) antibody [EPR2380] at 1/5000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : HeLa cell lysate treated with Calyculin A.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 108 kDa.Observed band size : 90-120 kDa .
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - delta 1 Catenin (phospho S268) antibody [EPR2380]; TA307608 at 1/100 dilution staining delta 1 Catenin in paraffin-embedded human breast carcinoma tissue by Immunohistochemistry.
Immunocytochemistry/ Immunofluorescence - delta 1 Catenin (phospho S268) antibody [EPR2380]; Immunofluorescent staining of delta 1 Catenin in A431 cells using TA307608 at 1/100 dilution.