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Home Antibody All anti-ANPEP antibodies

Anti-ANPEP Antibody EPR4059

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307567
  • Rabbit monoclonal antibody against CD13(clone EPR4059)
100ul 325 3-7 Days
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WB(1)
IHC(7)
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Also for ANPEP (NM_001150)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human CD13 was used as an immunogen.
Clone NameEPR4059 IsotypeTissue culture supernatant
Species ReactivityRat, Human (Does not react with: Mouse) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:100 - 1:250; ICC: 1:50 - 1:100
BufferDoes not react with Mouse. Is unsuitable for Flow Cyt.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt.

Reference Data

Target NameHomo sapiens alanyl (membrane) aminopeptidase (ANPEP)
Alternative NameAPN; CD13; GP150; LAP1; P150; PEPN
Database LinkNP_001141
Entrez Gene 290 Human
Entrez Gene 81641 Rat
FunctionAminopeptidase N is located in the small-intestinal and renal microvillar membrane, and it is also in other plasma membranes. In the small intestine, aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class show that CD13 and aminopeptidase N are identical. The latter enzyme is thought to be involved in the metabolism of regulatory peptides by diverse cell types such as small intestinal and renal tubular epithelial cells, macrophages, granulocytes, and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in CD13 appear to be a cause of various types of leukemia or lymphoma.
Related PathwayES Cell Differentiation/IPSTransmembraneProteaseDruggable Genome Glutathione metabolismMetabolic pathwaysRenin-angiotensin systemHematopoietic cell lineage

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - CD13 antibody [EPR4059]; All lanes : Anti-CD13 antibody [EPR4059] at 1/1000 dilution.Lane 1 : THP-1 cell lysate.Lane 2 : U937 cell lysate.Lane 3 : A375 cell lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 110 kDa.Observed band size : 150 kDa .
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD13 antibody [EPR4059]; Immunohistochemical staining of paraffin-embedded Human kidney tissue using TA307567 at a dilution of 1/100.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD13 antibody [EPR4059](TA307567); TA307567 showing positive staining in Prostatic carcinoma tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD13 antibody [EPR4059](TA307567); TA307567 showing positive staining in Normal liver tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD13 antibody [EPR4059](TA307567); TA307567 showing positive staining in Ovarian carcinoma tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD13 antibody [EPR4059](TA307567); TA307567 showing positive staining in Hepatocellular carcinoma tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD13 antibody [EPR4059](TA307567); TA307567 showing positive staining in Normal breast tissue.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-CD13 antibody [EPR4059](TA307567); TA307567 showing positive staining in Normal tonsil tissue.

 

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