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Anti-CITED2 Antibody EPR3416(2)
Also for CITED2 (NM_001168388)
|A synthetic peptide corresponding to residues in human CITED2 was used as an immunogen.|
|Human, Mouse, Rat
||0.5~1.0 mg/ml (Lot Dependent)
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Is unsuitable for Flow Cyt,ICC or IHC-P.
|Homo sapiens Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 (CITED2), transcript variant 2|
|ASD8; MRG-1; MRG1; P35SRJ; VSD2|
|CITED2 (Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2) is one of the founding members of a family of transcriptional modulators (1). As a CBP/p300-dependent transcription factor, it functions as a negative regulator of hypoxia inducible factor 1 (HIF-1)-mediated signaling by competing with HIF-1α for binding to CBP/p300 (1). Moreover, CITED2 physically interacts with the histone acetyltransferase p300/CB and coactivates DNA-binding transcription factors (2). Mutations in this protein are a cause of cardiac septal defects (3).|
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Western blot - CITED2 antibody [EPR3416(2)]; All lanes : Anti-CITED2 antibody [EPR3416(2)] at 1/1000 dilution.Lane 1 : Saos 2 cell lysate.Lane 2 : U937 cell lysate.Lane 3 : HeLa cell lysate.Lysates/proteins at 10 µg per lane.Predicted band size : 28 kDa.