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Home Antibody All anti-CALCA antibodies

Anti-CALCA Antibody EPR68(2)

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307516
  • Rabbit monoclonal antibody against Calcitonin(clone EPR68(2))
100ul 325 3-7 Days
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IHC(6)
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Also for CALCA (NM_001741)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human Calcitonin was used as an immunogen.
Clone NameEPR68(2) IsotypeIgG
Species ReactivityHuman, Mouse, Rat Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *IHC Suggested DilutionsIHC-P: 1:100 - 1:250
BufferpH: 7.40
Preservative: 0.01% Sodium azide
Constituents: 50% Glycerol, 0.05% BSA
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC/IF,IP or WB.

Reference Data

Target NameHomo sapiens calcitonin-related polypeptide alpha (CALCA), transcript variant 1
Alternative NameCALC1; CGRP; CGRP-I; CGRP1; CT; KC
Database LinkNP_001732
FunctionCalcitonin (Katacalcin) is a 32-amino acid polypeptide hormone that is commonly expressed in the parafollicular or C cells in the thyroid gland. It is also synthesized in a wide variety of other tissues, including the lung and intestinal tract (1). Calcitonin is a potent plasma calcium-lowering peptide; it decreases the level of calcium and phosphate in blood by promoting the incorporation of these ions in bones. Calcitonin staining is used in the identification of C cell proliferative abnormalities, such as C cell hyperplasia and invasive tumors (2). Staining for calcitonin may be used for the identification of a spectrum of C cell proliferative abnormalities ranging from C cell hyperplasia to invasive tumors (e.g. medullary thyroid carcinomas). Calcitonin activitiy might be exhibited in amyloid deposits within the tumor.
Related Pathway
Signaling by GPCR

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IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - Anti-Calcitonin antibody [EPR68(2)]; Immunohistochemical staining of Calcitonin in paraffin embedded Human medullary carcinoma of thyroid gland, using TA307516 at a 1/100 dilution.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Calcitonin antibody [EPR68(2)](TA307516); Immunohistochemical analysis of paraffin embedded Human Papillary carcinoma of thyroid gland tissue using TA307516 showing -ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Calcitonin antibody [EPR68(2)](TA307516); Immunohistochemical analysis of paraffin embedded Human Prostatic carcinoma tissue using TA307516 showing -ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Calcitonin antibody [EPR68(2)](TA307516); Immunohistochemical analysis of paraffin embedded normal Human tonsil tissue using TA307516 showing -ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Calcitonin antibody [EPR68(2)](TA307516); Immunohistochemical analysis of paraffin embedded Human Breast carcinoma tissue using TA307516 showing -ve staining.
IHC Image
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)-Anti-Calcitonin antibody [EPR68(2)](TA307516); Immunohistochemical analysis of paraffin embedded Human Glioma tissue using TA307516 showing -ve staining.

 

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