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Home Antibody All anti-CD72 antibodies

Anti-CD72 Antibody EPR3571

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SKU Description Amount Price Availability*  
TA307509
  • Rabbit monoclonal antibody against CD72 (clone EPR3571 )
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC400673) , 20ug Explanation
100ul $325 3-7 Days
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WB(1)

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human CD72 was used as an immunogen.
Clone NameEPR3571 IsotypeIgG
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsICC: 1:100, WB: 1:1000 - 5000,
Predicted MW Explanation 40 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens CD72 molecule (CD72)
Alternative NameCD72b; LYB2
Database LinkNP_001773
Entrez Gene 971 Human
FunctionCD72, a type II integral membrane glycopotein and a member of the C-type lectin family of cell surface receptors, is expressed in all stages of B cell development except in terminally differentiated plasma cells (1). Ligation of CD72 enhances B cell growth and differentiation. CD72 transmits positive signals through association with Grb2 and or CD19 and negative signals through association with SHP-1 (2 and 3). CD72 has been reported to bind to CD5, suggesting a role in regulating T-cell activation and proliferation (4). Disregulated expression of CD72 was related to disease such as lupus nephritis (5) and primary Sjögren’s syndrome (6).
Related PathwayES Cell Differentiation/IPSTransmembraneAdult stem cellsDruggable Genome B cell receptor signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - CD72 antibody [EPR3571]; Anti-CD72 antibody [EPR3571] at 1/1000 dilution + K562 cell lysate at 10 ug.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 40 kDa.
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