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Anti-CD72 Antibody EPR3571
Also for CD72 (NM_001782)
|A synthetic peptide corresponding to residues in human CD72 was used as an immunogen.|
||0.5~1.0 mg/ml (Lot Dependent)
||ICC: 1:100, WB: 1:1000 - 5000,
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Does not react with Mouse, Rat
|Homo sapiens CD72 molecule (CD72)|
|CD72, a type II integral membrane glycopotein and a member of the C-type lectin family of cell surface receptors, is expressed in all stages of B cell development except in terminally differentiated plasma cells (1). Ligation of CD72 enhances B cell growth and differentiation. CD72 transmits positive signals through association with Grb2 and or CD19 and negative signals through association with SHP-1 (2 and 3). CD72 has been reported to bind to CD5, suggesting a role in regulating T-cell activation and proliferation (4). Disregulated expression of CD72 was related to disease such as lupus nephritis (5) and primary Sjögren’s syndrome (6). |
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Western blot - CD72 antibody [EPR3571]; Anti-CD72 antibody [EPR3571] at 1/1000 dilution + K562 cell lysate at 10 µg.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 40 kDa.