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Anti-CD97 Antibody EPR4427
Also for CD97 (NM_001784)
|A synthetic peptide corresponding to residues in the extracellular domain of human CD97 was used as an immunogen.|
||Tissue culture supernatant
|Mouse, Human (Does not react with: Rat)
||Lot dependent; please refer to CoA along with shipment
||WB: 1:1000 - 1:10000; IP: 1:10 - 1:100; IHC-P: 1:250 - 1:500; ICC: 1:250 - 1:500
|Does not react with Rat. Is unsuitable for Flow Cyt.|
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
|Is unsuitable for Flow Cyt.
|Homo sapiens CD97 molecule (CD97), transcript variant 2|
Entrez Gene 976 Human
Entrez Gene 26364 Mouse
|CD97 is a member of the EGF-TM7 family of class II seven-span transmembrane (7-TM) molecules. It is a glycoprotein that is present on the surface of most activated leukocytes and spans the membrane seven times, which is a defining feature of G protein-coupled receptors. CD97 has an extended extracellular region with several N-terminal epidermal growth factor (EGF)-like domains, which mediate binding to its cellular ligand, decay accelerating factor (DAF, CD55), a regulatory protein of the complement cascade. The presence of structural features characteristic of extracellular matrix proteins and transmembrane proteins suggests that this protein is a receptor involved in both cell adhesion and signaling processes early after leukocyte activation.|
|GPCRSecreted ProteinES Cell Differentiation/IPSTransmembraneAdult stem cellsDruggable Genome |
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Western blot - CD97 antibody [EPR4427]; All lanes : Anti-CD97 antibody [EPR4427] at 1/1000 dilution.Lane 1 : Human tonsil lysate.Lane 2 : Jurkat cell lysate.Lane 3 : U937 cell lysate.Lane 4 : Human fetal thymus lysate.Lysates/proteins at 10 ug per lane.Predicted band size : 92 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD97 antibody [EPR4427]; TA307505 at 1/250 dilution staining CD97 in Human spleen by Immunohistochemistry, Paraffin-embedded tissue.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD97 antibody [EPR4427]; TA307505 at 1/250 dilution staining CD97 in Human colonic adenocarcinoma by Immunohistochemistry, Paraffin-embedded tissue.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - CD97 antibody [EPR4427]; TA307505 at 1/250 dilution staining CD97 in Human colonic tonsil by Immunohistochemistry, Paraffin-embedded tissue.