OriGene Technologies, Inc.
Search:    
Left ProductsProducts divider ServicesServices divider technologyTechnology divider researchResearch divider TechsupportTechSupport divider AboutAbout Right
 
Home Antibody All anti-ROR2 antibodies

Anti-ROR2 Antibody EPR3779

div

Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307281
  • Rabbit monoclonal antibody against ROR2(clone EPR3779)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC417906) , 20ug Explanation
100ul 325 In Stock
Add to Shopping Cart
WB(1)
IHC(1)
FC(1)
spacer
Also for ROR2 (NM_004560)
cDNA Clone shRNA/siRNA Primer Pair Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues of human ROR2 was used as an immunogen.
Clone NameEPR3779 IsotypeTissue culture supernatant
Species ReactivityHuman (Does not react with: Mouse, Rat) ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC, FC Suggested DilutionsWB: 1:1000 - 1:10000; ICC: 1:50 - 1:100; FC: 1:10 - 1:100
BufferDoes not react with Mouse, Rat. Is unsuitable for IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for IHC-P or IP.

Reference Data

Target NameHomo sapiens receptor tyrosine kinase-like orphan receptor 2 (ROR2)
Alternative NameBDB; BDB1; NTRKR2
Database LinkNP_004551
Entrez Gene 4920 Human
FunctionROR2 (receptor tyrosine kinase-like orphan receptor 2) is a tyrosine protein kinase receptor which is required for cartilage and growth plate development. As a member of the receptor protein kinases (RTKs) family, ROR2 is commonly found in embryonic kidney, but its function has not been fully understood. ROR2 has been linked to embryonic development due its involvement in WNT signaling pathway. Additionally, ROR2 has been shown to be critical for the formation of skeleton, heart, and genitals. Specifically, ROR2 phosphorylates 14-3-3 protein beta/alpha which leads to induction of osterogenesis and bone formation (2). A mutation in ROR2 is commonly seen in Robinow syndrome and autosomal dominant brachydactyly B disorders (3).
Related PathwayProtein KinaseTransmembraneDruggable Genome

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - ROR2 antibody [EPR3779]; All lanes : Anti-ROR2 antibody [EPR3779] at 1/1000 dilution.Lane 1 : HeLa cell lysate.Lane 2 : MCF-7 cell lysate.Lane 3 : SH-SY5Y cell lysate.Lane 4 : Saos-2 cell lysate.Lysates/proteins at 10 ug per lane.Secondary.HRP labelled goat anti-rabbit. at 1/2000 dilution.Predicted band size : 105 kDa.
IHC Image
Immunohistochemistry (Frozen sections) - Anti-ROR2 antibody [EPR3779]; TA307281 staining ROR2 in Mouse cartilage precursor to endochondral bone tissue by Immunohistochemistry (Frozen sections). The sections were PFA-fixed prior to blocking with 20% serum for 1 hour at 19°C and permeabilization with 0.1% Triton. The primary antibody was diluted 1/50 and incubated with the sample for 16 hours at 4°C. An Alexa Fluor? 647-conjugated Rabbit polyclonal was used as the secondary antibody, diluted 1/200. DAPI was used for the blue counterstain.
FC Image
Flow Cytometry - ROR2 antibody [EPR3779]; Flow cytometric analysis of Hela cells using TA307281 at 1/10 dilution (red) or a rabbit IgG (negative) (green).

 

spacer
Inc 5000 Healthcare Company Copyright © 2014 OriGene Technologies, Inc. All Rights Reserved. Legal Notices.
9620 Medical Center Dr., Suite 200, Rockville, MD 20850 • 1.888.267.4436

Reproduction of any materials from this website is strictly forbidden without permission.

All Products by: Title | Price | Category | Popularity | Best Sellers Topselling Products by: Title | Price | Category | Popularity | Favorites
Popular Categories: Popularity | Our Choices | All-Round Favorites | Title Topselling Categories: Popularity | Our Choices | All-Round Favorites | Title