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Home Antibody All anti-PAX5 antibodies

Anti-PAX5 Antibody EPR3729

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307082
  • Rabbit monoclonal antibody against PAX5(clone EPR3729)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC413830) , 20ug
100ul $325 3-7 Days
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WB(1)
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Also for PAX5 (NM_016734)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues in human PAX5 was used as an immunogen.
Clone NameEPR3729 IsotypeIgG
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsICC: 1: 100 - 250, WB: 1: 1,000 - 10,000,
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Does not react with Mouse, Rat

Reference Data

Target NameHomo sapiens paired box 5 (PAX5), transcript variant 1
Alternative NameALL3; BSAP
Database LinkNP_057953
FunctionThe human paired box protein Pax-5 (PAX5) is a member of the paired box domain family of transcription factors that play a role in B-cell differentiation, neural development, and spermatogenesis (1). As a result, its expression is detected in the developing central nervous system (CNS) and testis (1). In particular, PAX5 is essential for maintaining the identity and function of mature B cells during late B lymphopoiesis (2). The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation (3). During B-cell differentiation, PAX5 interacts with DAXX, a bridge protein that helps PAX5 to function as both a transcriptional activator and a repressor (4). A chromosomal aberration involving PAX5 is a cause of acute lymphoblastic leukemia (1).
Related Pathway

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WB Image
Western blot - PAX5 antibody [EPR3729]; All lanes : Anti-PAX5 antibody [EPR3729] at 1/1000 dilution.Lane 1 : Ramos cell lysate.Lane 2 : Daudi cell lysate.Lysates/proteins at 10 µg per lane.Secondary.HRP labelled goat anti-rabbit at 1/2000 dilution.Predicted band size : 42 kDa.

 

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