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Anti-APOA2 Antibody EP2912

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA307004
  • Rabbit monoclonal antibody against Apolipoprotein A-II (ApoA-II)(clone EP2912)
  • FREE positive control: HEK293T cell transient overexpression lysate (LC400619) , 20ug
100ul $325 3-7 Days
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OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus region of human Apolipoprotein A-II (ApoA-II) was used as an immunogen.
Clone NameEP2912 IsotypeTissue culture supernatant
Species ReactivityHuman Concentration0.5~1.0 mg/ml (Lot Dependent)
Guaranteed Application *WB Suggested DilutionsWB: 1:1000 - 1:10000
BufferDoes not react with Mouse, Rat. Is unsuitable for Flow Cyt,ICC,IHC-P or IP.
Purification PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Note Is unsuitable for Flow Cyt,ICC,IHC-P or IP.

Reference Data

Target NameHomo sapiens apolipoprotein A-II (APOA2)
Alternative NameApo-AII; ApoA-II; apoAII
Database LinkNP_001634
FunctionApolipoprotein A II is the second most abundant protein of the high density lipoprotein particles, accounting for 20% of protein mass of HDL. The concentration of ApoA-I and ApoA-II is inversely correlated with the frequency of heart disease in human (1). In studies with mice and humans, ApoA-II levels have been associated with increased susceptibility to atherosclerosis, increased free fatty acid levels, increased body fat, and increased insulin resistance (2). ApoA-II consists of three potential amphipathic helices of 17 residues each, which contribute to the lipid-binding properties of this apolipoprotein (3). Currently, the best characterized activity of apoA-II is its potent antagonism of the anti-atherogenic and anti-inflammatory activities of ApoA-I, probably due to its competition with the latter for lipid acyl side chains of HDL (1).
Related Pathway

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WB Image
Western blot - Anti-Apolipoprotein A II antibody [EP2912]; Anti-Apolipoprotein A II antibody [EP2912] at 1/1000 dilution + Human plasma lysate at 10 µg.Predicted band size : 11 kDa.

 

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