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Anti-PRMT1 Antibody EPR3292
Also for PRMT1 (NM_198319)
|A synthetic peptide corresponding to residues in human PRMT1 was used as an immunogen.|
|Mouse, Human (Does not react with: Rat)
||Lot dependent; please refer to CoA along with shipment
||IHC: 1:100 - 250, WB: 1:5000 - 10,000,
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Tissue culture supernatant
|Does not react with Rat
|Homo sapiens protein arginine methyltransferase 1 (PRMT1), transcript variant 2|
|ANM1; HCP1; HRMT1L2; IR1B4;6720434D09Rik; AW214366; Hrmt1l2; Mrmt1; OTTMUSP00000022387; arginine N-methyltransferase 1; heterogeneous nuclear ribonucleoproteins methyltransferase-like 2; protein arginine N-methyltransferase 1|
Entrez Gene 3276 Human
Entrez Gene 15469 Mouse
|PRMT1 is a member of the Protein arginine methyltransferases (PRMTs) family that regulates mRNA processing and maturation by modulating the activity of RNA-binding proteins through methylation (1). PRMTs have been implicated in a variety of processes, including cell proliferation, signal transduction, and protein trafficking. Eleven PRMTs have been identified in humans. Except for PRMT2, 10 and 11, all PRMTs have been shown to catalyze arginine methylation, with PRMT1, 4, 5, 7, 8 and 9 have the ability to also methylate histones (2). PRMT1 appears to be a major type I enzyme in embryonic stem cells, and in wild-type cells, most substrates of the enzyme appear to be maintained in a fully methylated state (3). |
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Western blot - PRMT1 antibody [EPR3292]; All lanes : Anti-PRMT1 antibody [EPR3292] at 1/5000 dilution.Lane 1 : A549 cell lysate.Lane 2 : HeLa cell lysate.Lane 3 : NIH/3T3.Lysates/proteins at 10 ug per lane.Predicted band size : 42 kDa.
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) - PRMT1 antibody [EPR3292]; Immunohistochemical analysis of paraffin-embedded Human breast cancer tissue using TA306980 at 1/100 dilution.