Home Antibody All anti-C1QTNF6 antibodies
Also for C1QTNF6 (NM_031910)
|CTRP6 antibody was raised against a 15 amino acid peptide from near the carboxy-terminus of human CTRP6.|
||ELISA, WB: 1 and 2 ug/ml, ICC, IF: 20 ug/ml
|PBS containing 0.02% sodium azide.|
|Affinity chromatography purified via peptide column (Protein A or G Sepharose)
|Homo sapiens C1q and tumor necrosis factor related protein 6 (C1QTNF6), transcript variant 1|
|CTFP6; CTRP6; ZACRP6|
|Adipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-?-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). CTRP6 contains at least 4 glycosylation motifs, suggesting that CTRP6 may be highly post-translationally modified (3).|
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Western blot analysis of CTRP6 in HeLa cell lysate with CTRP6 antibody at (A) 1 and (B) 2 ug/mL.
Immunocytochemistry of CTRP6 in HeLa cells with CTRP6 antibody at 10 ug/mL.