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Home Antibody All anti-C1QTNF2 antibodies

Anti-C1QTNF2 Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA306231 Rabbit Polyclonal CTRP2 Antibody 100ug $325 3-7 Days
LC403129 C1QTNF2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
IHC(1)

OriGene Data

ImmunogenRabbit CTRP2 polyclonal antibody was raised against a 16 amino acid peptide from near the center of human CTRP2.
Clone Name IsotypeIgG
Species ReactivityHuman, Mouse Concentration1ug/ul
Guaranteed Application *WB, IHC Suggested DilutionsWB: 2 - 4 ug/ml
BufferPBS containing 0.02% sodium azide.
Purification Affinity chromatography purified via peptide column

Reference Data

Target NameHomo sapiens C1q and tumor necrosis factor related protein 2 (C1QTNF2)
Alternative NameCTRP2; zacrp2
Database LinkNP_114114
Entrez Gene 114898 Human
Entrez Gene 69183 Mouse
FunctionAdipose tissue of an organism plays a major role in regulating physiologic and pathologic processes such as metabolism and immunity by producing and secreting a variety of bioactive molecules termed adipokines (reviewed in 1). One highly conserved family of adipokines is adiponectin/ACRP30 and its structural and functional paralogs, the C1q/tumor necrosis factor-?-related proteins (CTRPs) 1-7 (2). Unlike adiponectin, which is expressed exclusively by differentiated adipocytes, the CTRPs are expressed in a wide variety of tissues (3). These proteins are thought to act mainly on liver and muscle tissue to control glucose and lipid metabolism. An analysis of the crystal structure of adiponectin revealed a structural and evolutionary link between TNF and C1q-containing proteins, suggesting that these proteins arose from a common ancestral innate immunity gene (4). Of the CTRPs, CTRP2 is most similar structurally and functionally to adiponectin. Recombinant CTRP2 rapidly activated AMPK and MAPK in cultured C2C12 cells, leading to increased glycogen accumulation and fatty acid oxidation (3).
Related PathwaySecreted Protein

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of CTRP2 in 3T3 (Balb) cell lysate with CTRP2 (IN) antibody at (A) 1, (B) 2, and (C) 4 ug/ml.
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Immunohistochemical staining of human brain tissue using CTRP2 antibody at 10 ug/ml.
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