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Home Antibody All anti-TLR4 antibodies

Anti-TLR4 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA306126 Rabbit Polyclonal TLR4 Antibody 100ug $325 3-7 Days
LC408575 TLR4 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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OriGene Data

ImmunogenTLR4 antibody was raised against a peptide corresponding to 15 amino acids near the amino-terminus of human TLR4.
Clone Name IsotypeIgG
Species ReactivityHuman Concentration1ug/ul
Guaranteed Application *WB, IF Suggested DilutionsWB: 2.5 - 5 ug/mL, ICC: 2 ug/mL
BufferPBS containing 0.02% sodium azide.
Purification Ion exchange chromatography purified

Reference Data

Target NameHomo sapiens toll-like receptor 4 (TLR4), transcript variant 3
Alternative NameARMD10; CD284; TLR-4; TOLL
Database LinkNP_003257
Entrez Gene 7099 Human
FunctionToll-like receptors (TLRs) are signaling molecules that recognize different microbial products during infection and serve as an important link between the innate and adaptive immune responses (1-3). These proteins act through adaptor molecules such as MyD88 and TIRAP to activate various kinases and transcription factors such as Protein Kinase C (PKC) alpha/beta and NF-kappaB (4-6). Studies with TLR4-deficient mice indicate that the main ligand for TLR is lipopolysaccharide. Consequently, these mice also showed increased susceptibility to Gram-negative sepsis (7).
Related PathwayTransmembraneDruggable Genome Toll-like receptor signaling pathwayPathogenic Escherichia coli infection

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot analysis of TLR4 in PC-3 cell lysates with TLR4 antibody at (A) 2.5 and (B) 5 ug/mL.

IF Image
Immunocytochemistry of TLR4 in K562 cells with TLR4 antibody at 2 ug/mL.


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