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Home Antibody All anti-MAPKAPK2 antibodies

Anti-MAPKAPK2 Antibody E341

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SKU Description Amount Price Availability*  
TA303762 Rabbit monoclonal antibody against MAPKAP Kinase-2 (E341) 100ul $325 In Stock
LC417772 MAPKAPK2 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(2)
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Also for MAPKAPK2 (NM_004759)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near C-terminus of human MAPKKAP Kinase-2 was used as immunogen.
Clone NameE341 IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsWB: 1:500-1,000; IP: 1:200
Predicted MW Explanation 46 kDa
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification IgG fraction

Reference Data

Target NameHomo sapiens mitogen-activated protein kinase-activated protein kinase 2 (MAPKAPK2), transcript variant 1
Alternative NameMAPKAP-K2; MK-2; MK2
Database LinkNP_004750
Entrez Gene 9261 Human
Entrez Gene 17164 Mouse
Entrez Gene 289014 Rat
FunctionThis gene encodes a member of the Ser/Thr protein kinase family. This kinase is regulated through direct phosphorylation by p38 MAP kinase. In conjunction with p38 MAP kinase, this kinase is known to be involved in many cellular processes including stress and inflammatory responses, nuclear export, gene expression regulation and cell proliferation. Heat shock protein HSP27 was shown to be one of the substrates of this kinase in vivo. Two transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq].
Related PathwayProtein KinaseDruggable Genome MAPK signaling pathwayVEGF signaling pathwayNeurotrophin signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot - MAPKAP Kinase 2 antibody [E341]; Anti-MAPKAP Kinase 2 antibody [E341] at 1/1000 dilution + Hela cell lysate.Predicted band size : 46 kDa.Observed band size : 46 kDa.
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Western blot - Anti-MAPKAP Kinase 2 antibody; Lanes 1 - 2 : Anti-MAPKAP Kinase 2 (phospho T334) antibodyat 1:500.Lanes 3 - 4 : Anti-MAPKAP Kinase 2 antibodyat 1:500.Lane 1 : UV treated HeLa cells.Lane 2 : UV treated HeLa cells + p38 inhibitor.Lane 3 : UV treated HeLa cells.Lane 4 : UV treated HeLa cells + p38 inhibitor.Secondary.IRDye 680 LICOR goat anti-rabbit.Performed under reducing conditions.
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