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Home Antibody All anti-BMPR1A antibodies

Anti-BMPR1A Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA303097 Goat Polyclonal Antibody against BMPR1A 100ug $325 In Stock
LC418061 BMPR1A HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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WB(1)
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Also for BMPR1A (NM_004329)
cDNA Clone shRNA/siRNA CRISPR KO Kit Protein Antibody

OriGene Data

Immunogen Peptide with sequence C-KSDSDQKKSEN, from the internal region of the protein sequence according to NP_004320.2.
Clone Name IsotypeGoat IgG
Species ReactivityTest: Human. Expected from seq similarity: Human, Dog ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB Suggested DilutionsELISA: 1:16,000. WB: 1-3µg/ml.
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.

Reference Data

Target NameHomo sapiens bone morphogenetic protein receptor, type IA (BMPR1A)
Alternative Name10q23del; ACVRLK3; ALK3; CD292; SKR5
Database LinkNP_004320
Entrez Gene 657 Human
Entrez Gene 489077 Dog
FunctionThe bone morphogenetic protein (BMP) receptors are a family of transmembrane serine/threonine kinases that include the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. These receptors are also closely related to the activin receptors, ACVR1 and ACVR2. The ligands of these receptors are members of the TGF-beta superfamily. TGF-betas and activins transduce their signals through the formation of heteromeric complexes with 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. [provided by RefSeq].
Related PathwayProtein KinaseES Cell Differentiation/IPSTransmembraneDruggable Genome Cytokine-cytokine receptor interactionTGF-beta signaling pathway

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

TA303097 (1µg/ml) staining of HeLa cell lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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