Home Antibody All anti-TXNRD1 antibodies
Also for TXNRD1 (NM_001093771)
| Peptide with sequence TKRSGASILQAGC, from the C Terminus of the protein sequence according to NP_003321.|
|Test: Human. Expected from seq similarity: Human, Pig
||ELISA: 1:32,000. WB: 0.1-1µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
| Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens thioredoxin reductase 1 (TXNRD1), transcript variant 5|
|GRIM-12; TR; TR1; TRXR1; TXNR|
Entrez Gene 7296 Human
|This gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein reduces thioredoxins as well as other substrates, and plays a role in selenium metabolism and protection against oxidative stress. The functional enzyme is thought to be a homodimer which uses FAD as a cofactor. Each subunit contains a selenocysteine (Sec) residue which is required for catalytic activity. The selenocysteine is encoded by the UGA codon that normally signals translation termination. The 3' UTR of selenocysteine-containing genes have a common stem-loop structure, the sec insertion sequence (SECIS), that is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. Alternative splicing results in several transcript variants encoding the same or different isoforms. [provided by RefSeq]. |
|Druggable Genome Pyrimidine metabolism|
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TA302806 staining (0.1µg/ml) of Human Placenta lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence.