p27 KIP 1 (CDKN1B) Goat Polyclonal Antibody

CAT#: TA302712

Goat Polyclonal Antibody against CDKN1B


USD 465.00

5 Days*

Size
    • 100 ug

Product Images

Frequently bought together (3)
Transient overexpression lysate of cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B)
    • 100 ug

USD 436.00


beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

USD 200.00


Recombinant protein of human cyclin-dependent kinase inhibitor 1B (p27, Kip1) (CDKN1B), 20 µg
    • 20 ug

USD 867.00

Other products for "p27 KIP 1"

Specifications

Product Data
Applications WB
Recommended Dilution ELISA: 1:32,000. WB: 1-3µg/ml.
Reactivities Human (Expected from sequence similarity: Mouse, Rat, Cow, Dog)
Host Goat
Isotype IgG
Clonality Polyclonal
Immunogen Peptide with sequence C-EQTPKKPGLRRRQT, from the C Terminus of the protein sequence according to NP_004055.1.
Formulation Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration lot specific
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
Conjugation Unconjugated
Storage Store at -20°C as received.
Stability Stable for 12 months from date of receipt.
Gene Name cyclin-dependent kinase inhibitor 1B
Background This gene encodes a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state. [provided by RefSeq]
Synonyms CDKN4; KIP1; MEN1B; MEN4; P27KIP1
Reference Data
Protein Families Druggable Genome
Protein Pathways Cell cycle, Chronic myeloid leukemia, ErbB signaling pathway, Pathways in cancer, Prostate cancer, Small cell lung cancer

{0} Product Review(s)

0 Product Review(s) Submit review

Be the first one to submit a review

Product Citations

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.