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Home Antibody All anti-APPL1 antibodies

Anti-APPL1 Antibody


Specifications Citations Customer Reviews Product Documents
SKU Description Amount Price Availability*  
TA302413 Goat Polyclonal Antibody against APPL1 100ug $325 3-7 Days
LC402145 APPL1 HEK293T cell transient overexpression lysate (as WB positive control) 20ug $50 In Stock
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Also for APPL1 (NM_012096)
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OriGene Data

ImmunogenPeptide with sequence C-NRYSRLSKKRENDK, from the internal region of the protein sequence according to NP_036228.1.
Clone Name IsotypeGoat IgG
Species ReactivityExpected from seq similarity: Human, Mouse, Rat, Dog, Cow Concentration0.5 mg/ml
Guaranteed Application *WB Suggested DilutionsELISA: 1:64,000. WB: 0.3-1µg/ml.
Predicted MW Explanation 83295Da
BufferSupplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Purification Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.

Reference Data

Target NameHomo sapiens adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 (APPL1)
Alternative NameAPPL; DIP13alpha
Database LinkNP_036228
Entrez Gene 26060 Human
Entrez Gene 72993 Mouse
Entrez Gene 290537 Rat
Entrez Gene 484716 Dog
FunctionThe protein encoded by this gene has been shown to be involved in the regulation of cell proliferation, and in the crosstalk between the adiponectin signalling and insulin signalling pathways. The encoded protein binds many other proteins, including RAB5A, DCC, AKT2, PIK3CA, adiponectin receptors, and proteins of the NuRD/MeCP1 complex. This protein is found associated with endosomal membranes, but can be released by EGF and translocated to the nucleus. [provided by RefSeq].
Related Pathway Pathways in cancerColorectal cancer

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
TA302413 (0.5µg/ml) staining of 1) Rat Aortic Smooth Muscle cell lysate 2) after infection with Human APPL1 adenovirus for 48hrs. Detected by chemiluminescence. Data kindly provided by Dr. L. Jia, Ann Arbor, USA.


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