Home Antibody All anti-RPS6KB2 antibodies
Also for RPS6KB2 (NM_003952)
|This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human p70 S6Kbeta Antibody.|
||WB: 1:50~100; IHC: 1:50-100; ELISA: 1: 1,000;
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.|
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. (Protein A or G Sepharose)
|Homo sapiens ribosomal protein S6 kinase, 70kDa, polypeptide 2 (RPS6KB2)|
|KLS; p70(S6K)-beta; P70-beta; P70-beta-1; P70-beta-2; p70S6Kb; S6K-beta2; S6K2; SRK; STK14B|
|This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates the S6 ribosomal protein and eucaryotic translation initiation factor 4B. Phosphorylation of S6 leads to an increase in protein synthesis and cell proliferation.|
TGF Beta Signaling Pathway
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(LEFT)Western blot analysis of anti-p70 S6Kbeta Antibody (N-term) Pab in HepG2 cell line lysates (35ug/lane). RPS6KB2(arrow) was detected using the purified Pab (1:60 dilution). (RIGHT)Western blot analysis of anti-p70 S6Kbeta Antibody (N-term) Pab in 293 cell line lysates transiently transfected with the RPS6KB2 gene (2ug/lane). p70 S6Kbeta(arrow) was detected using the purified Pab (1:60 dilution).
Formalin-fixed and paraffin-embedded human breast carcinoma reacted with p70 S6Kbeta Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.