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Home Antibody All anti-F11R antibodies

Anti-F11R Antibody EP1042Y

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300750
  • Rabbit Monoclonal Antibody against F11R (Clone EP1042Y)
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC403392) , 20ug
100ul 325 3-7 Days
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WB(1)
IHC(1)
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Also for F11R (NM_144504)
cDNA Clone shRNA/siRNA Lysate Protein Antibody

OriGene Data

ImmunogenA synthetic peptide corresponding to residues near the N-terminus of human JAM1 was used as an immunogen.
Clone NameEP1042Y IsotypeIgG
Species ReactivityMouse, Rat, Human ConcentrationLot dependent; please refer to CoA along with shipment
Guaranteed Application *WB, IHC Suggested DilutionsWB: 1:1000 - 1:10000; IHC-P: 1:100 - 1:250
BufferPBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%
Purification Tissue culture supernatant
Note Is unsuitable for Flow Cyt,ICC or IP.

Reference Data

Target NameHomo sapiens F11 receptor (F11R), transcript variant 5
Alternative NameJAM, KAT, JAM1, JAMA, JCAM, CD321, JAM-1, JAM-A, PAM-1
Database LinkNP_653087
FunctionJunctional Adhesion Molecules (JAMs) are components and regulators of the well-characterized epithelial and endothelial tight junction. JAM is selectively concentrated at intercellular junctions of endothelial and epithelial cells of different origins. Microscopy shows that JAM codistributes with tight junction components at the apical region of the intercellular cleft. A mAb directed to JAM (BV11) was found to inhibit spontaneous and chemokine-induced monocyte transmigration through an endothelial cell monolayer in vitro. Systemic treatment of mice with BV11 mAb blocked monocyte infiltration upon chemokine administration in subcutaneous air pouches (1). The human protein shares a highly conserved structure and sequence with the murine protein. However it is distinct in that it is constitutively expressed on circulating neutrophils, monocytes, platelets and lymphocyte subsets (2).
Related Pathway
Hemostasis

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

WB Image
Western blot - Junctional Adhesion Molecule 1 antibody [EP1042Y]; Anti-Junctional Adhesion Molecule 1 antibody [EP1042Y] at 1/2000 dilution + Hela cell lysate at 10 ug.Secondary.Goat anti-rabbit HRP labeled at 1/2000 dilution.Predicted band size : 33 kDa.Observed band size : 33 kDa.
IHC Image
Immunohistochemistry (Paraffin-embedded sections) - Junctional Adhesion Molecule 1 antibody [EP1042Y]; Immunohistochemical staining of paraffin-embedded human liver using TA300750 at a 1/100 dilution.

 

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