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Anti-BCL6 Antibody EP529Y
Also for BCL6 (NM_001706)
|A synthetic peptide corresponding to residues in the C-term of human Bcl-6 was used as immunogen.|
|Human (Does not react with: Mouse, Rat)
||Lot dependent; please refer to CoA along with shipment
||IP: 1:50; WB: 1:500 - 1:2000; ICC: 1:100 - 1:250; ICC/IF: Use at an assay dependent concentration; IHC-P: Use at an assay dependent concentration
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Is unsuitable for Flow Cyt.
|Homo sapiens B-cell CLL/lymphoma 6 (BCL6), transcript variant 1|
|BCL5; BCL6A; LAZ3; ZBTB27; ZNF51|
Entrez Gene 604 Human
|Bcl-6 (also known as LAZ3) is a member of the POZ/zinc finger (POK) family that contains an N-terminal POZ domain and 6 C-terminal zinc finger motifs (1). Bcl-6 is a transcriptional regulator that plays an important role in lymphocyte, myocyte, male germ cells, and keratinocyte survival and or differentiation (2-3). Bcl-6 has also been found to repress a number of genes involved in B cell activation and terminal differentiation, inflammation and cell cycle regulation (4). Chromosomal aberration in Bcl-6 may be a cause of B-cell non –Hodgkin lymphoma and B-cell leukemia (5). |
|Transcription FactorsDruggable Genome |
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Western blot - Bcl6 antibody [EP529Y]; Anti-Bcl6 antibody [EP529Y] at 1/2000 dilution + Daudi cell lysate.Predicted band size : 78 kDa.Observed band size : 85-90 kDa .