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Anti-PDGFRB Antibody Y92
Also for PDGFRB (NM_002609)
|A synthetic peptide corresponding to residues in C-terminus of human PDGF receptor- ß was used as immunogen. The antibody does not cross-react with other CSF-1/PDGF receptor family members.|
|Mouse, Rat, Human
||Lot dependent; please refer to CoA along with shipment
|WB, IHC, IF
||WB: 1: 10,000; IHC: 1: 100; ICC: 1: 100; IP: 1:30
|PBS 49%,Sodium azide 0.01%,Glycerol 50%,BSA 0.05%|
|Homo sapiens platelet-derived growth factor receptor, beta polypeptide (PDGFRB)|
|CD140B; IBGC4; IMF1; JTK12; PDGFR; PDGFR-1; PDGFR1|
Entrez Gene 5159 Human
Entrez Gene 18596 Mouse
Entrez Gene 24629 Rat
|Human platelet-derived growth factor (PDGF) receptor, is a receptor tyrosine kinase whose activity induces various signalling cascades leading to cell growth and proliferation. Two major isoforms exist, PDGF receptor-a and PDGF receptor-ß. PDGF receptor-ß can only bind two specific PDGF isoforms, PDGF-ß and PDGF-? (1,2). Upon ligand binding, the receptor undergoes autophosphorylation, allowing binding and activation of cytoplasmic SH2 domain-containing signal transduction molecules such as PI kinase (3), Grb2, and Src, among others.|
|Protein KinaseES Cell Differentiation/IPSTransmembraneDruggable Genome MAPK signaling pathwayCalcium signaling pathwayCytokine-cytokine receptor interactionFocal adhesionGap junctionRegulation of actin cytoskeletonMore Pathways >> |
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Western blot - PDGF Receptor beta antibody [Y92]; Anti-PDGF Receptor beta antibody [Y92] + NIH 3T3 cell lysate.Predicted band size : 124 kDa.Observed band size : 175 kDa .
Immunohistochemistry (Paraffin-embedded sections) - PDGF Receptor beta antibody [Y92]; Immunofluorescence analysis of NIH3T3 cells stimulated with PDGF, staining PDGF Receptor beta with TA300416.
Immunocytochemistry/ Immunofluorescence - PDGF Receptor beta antibody [Y92]; Immunofluorescence analysis of NIH3T3 cells stimulated with PDGF, staining PDGF Receptor beta with TA300416.
Immunocytochemistry/ Immunofluorescence - Anti-PDGF Receptor beta antibody [Y92]; Immunofluorescence analysis of NIH3T3 cells stimulated with PDGF, staining PDGF Receptor beta with TA300416.