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Home Antibody All anti-APP antibodies

Anti-APP Antibody

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Specifications Citations (0) Related Products Product Documents
SKU Description Amount Price Availability*  
TA300060
  • Rabbit Polyclonal Antibody against APP
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424694) , 20ug Explanation
100ug $325 In Stock

Buy any antibody of 100ul or more, get a free package of 3 loading control antibody samples. View Details Add to Shopping Cart

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WB(2)

OriGene Data

ImmunogenThis APP antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 736-770 amino acids from the C-terminal region of human APP.
Clone Name IsotypeIgG
Species ReactivityHuman (Predicted: Mouse, Rat, Pig, Monkey) Concentration0.25 mg/ml
Guaranteed Application *WB Suggested DilutionsWB: 1:1000
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reference Data

Target NameHomo sapiens amyloid beta (A4) precursor protein (APP), transcript variant 1
Alternative NameAAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2
Database LinkNP_000475
Entrez Gene 351 Human
Entrez Gene 11820 Mouse
Entrez Gene 54226 Rat
Entrez Gene 100427716 Monkey
FunctionAPP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).
Related PathwayTransmembraneDruggable Genome Alzheimer's disease

* Availability is in business days
* OriGene provides validated application data and protocol, with money back guarantee.

Western blot analysis of APP (arrow) using rabbit polyclonal APP Antibody (C-term) (Cat. #TA300060). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the APP gene (Lane 2) (Origene Technologies).
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Western blot analysis of APP (arrow) using rabbit polyclonal APP Antibody (C-term) (Cat. #TA300060). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the APP gene (Lane 2) (Origene Technologies).
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