Home Antibody All anti-APP antibodies
|This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human APP.|
||WB: 1:50~100; ELISA: 1: 1,000
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.|
|This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
|Homo sapiens amyloid beta (A4) precursor protein (APP), transcript variant 1|
|AAA; ABETA; ABPP; AD1; APPI; CTFgamma; CVAP; PN-II; PN2|
|APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).|
Delta-Notch Signaling Pathway
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Western blot analysis of APP (arrow) using rabbit polyclonal APP Antibody (C-term) (Cat. #TA300060). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the APP gene (Lane 2).