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Anti-TEK Antibody

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Specifications Citations Related Products Product Documents
SKU Description Amount Price Availability*  
TA300046
  • TEK (C-term ) Rabbit Polyclonal Antibody
  • Free Sample of Positive Control: HEK293T cell transient overexpression lysate (LC424703) , 20ug
100ug 325 In Stock
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WB(1)

OriGene Data

ImmunogenThis antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from aa 773~789 of human TEK.
Clone Name IsotypeIg
Species ReactivityHuman ConcentrationLot Dependent
Guaranteed Application *WB Suggested DilutionsWB: 1:2000
BufferPurified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Reference Data

Target NameHomo sapiens TEK tyrosine kinase, endothelial (TEK), transcript variant 1
Alternative NameCD202B; TIE-2; TIE2; VMCM; VMCM1
Database LinkNP_000450
FunctionThe TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.
Related Pathway
Hemostasis

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WB Image
Western blot analysis of TEK (arrow) using rabbit polyclonal TEK Antibody (C-term)(TA300046). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the TEK gene (Lane 2) (Origene Technologies).

 

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