Home Antibody All anti-TEK antibodies
|This antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from aa 773~789 of human TEK.|
|Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.|
|This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
|Homo sapiens TEK tyrosine kinase, endothelial (TEK), transcript variant 1|
|CD202B; TIE-2; TIE2; VMCM; VMCM1|
|The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations; the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.|
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Western blot analysis of TEK (arrow) using rabbit polyclonal TEK Antibody (C-term)(TA300046). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the TEK gene (Lane 2) (Origene Technologies).