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Also for KLK5 (NM_001077491)
|Peptide with sequence KAGRDSCQGD, from the internal region of the protein sequence according to NP_036559.1; NP_001070959.1; NP_001070960.1.|
|Test: Human. Expected from seq similarity: Human;Rat, Dog, Cow
||ELISA: 1:4,000. WB: 0.1-0.3µg/ml.
|Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.|
|Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Supplied at 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin. Aliquot and store at -20°C. Minimize freezing and thawing.
|Homo sapiens kallikrein related peptidase 5 (KLK5), transcript variant 2|
|KLK-L2; KLKL2; SCTE|
Entrez Gene 25818 Human
Entrez Gene 102546758 Rat
Entrez Gene 484353 Dog
|Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its expression is up-regulated by estrogens and progestins. The encoded protein is secreted and may be involved in desquamation in the epidermis. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq].|
|Secreted ProteinTransmembraneProteaseDruggable Genome |
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TA303202 (0.1µg/ml) staining of Human Prostate lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.