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Also for UCHL1 (NM_004181)
|Recombinant full length human UCHL1 purified from E. coli|
|bovine, human, rat
||Lot dependent; please refer to CoA along with shipment
||WB: 1:5,000, IF: 1:500
|total IgG fraction + 10 mM NaN3.|
|Total IgG fraction
|Homo sapiens ubiquitin C-terminal hydrolase L1 (UCHL1)|
|HEL-117; NDGOA; PARK5; PGP 9.5; PGP9.5; PGP95; Uch-L1|
Entrez Gene 7345 Human
Entrez Gene 29545 Rat
|The protein encoded by this gene belongs to the peptidase C12 family. This enzyme is a thiol protease that hydrolyzes a peptide bond at the C-terminal glycine of ubiquitin. This gene is specifically expressed in the neurons and in cells of the diffuse neuroendocrine system. Mutations in this gene may be associated with Parkinson disease.|
|ProteaseDruggable Genome Parkinson's disease|
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Western blot of rat hippocampal homogenate showing specific immunolabeling of the ~ 24k UCHL1 protein.
Rat mixed neuron/glial cultures stained with anti-UCHL1 antibody (green) and rabbit anti-GFAP antibody (cat. #620-GFAP) (red). Blue is a DNA stain.