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Anti-RHO Antibody 4D2
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|Human, mouse, rat, Bovine, porcine
||ICC, IHC, IP, WB, ELISA
|TBS, 50% glycerol, 0.09% sodium azide|
|Homo sapiens rhodopsin (RHO)|
|CSNBAD1; OPN2; RP4|
Entrez Gene 6010 Human
Entrez Gene 212541 Mouse
Entrez Gene 24717 Rat
|Retinitis pigmentosa is an inherited progressive disease which is a major cause of blindness in western communities. It can be inherited as an autosomal dominant, autosomal recessive, or X-linked recessive disorder. In the autosomal dominant form,which comprises about 25% of total cases, approximately 30% of families have mutations in the gene encoding the rod photoreceptor-specific protein rhodopsin. This is the transmembrane protein which, when photoexcited, initiates the visual transduction cascade. Defects in this gene are also one of the causes of congenital stationary night blindness. [provided by RefSeq].|
|TransmembraneDruggable Genome |
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Immunofluorescence of Rho using a dilution of Rhodopsin antibody